P266. Emotional and functional status in Spanish Crohn's disease patients

M. Iglesias1, F. Gomollón2, Y. Gonzalez-Lama3, J. Hinojosa4, M. Maroto5, F. Muñoz6, I. Perez7, L. Oltra4, M. Aceituno8, T. Castro9

1FIENAD, Santiago de Compostela, Spain; 2Hospital Clinico Universitario Lozano Blesa, Zaragoza, Spain; 3Hospital Universitario Puerta de Hierro, Gastroenterology, Madrid, Spain; 4Hospital de Manises, Valencia, Spain; 5Hospital de Cruces, Bilbao, Spain; 6Hospital de León, León, Spain; 7ACCU-España, Spain; 8Hospital Clinic, Barcelona, Spain; 9Hospital General de Jerez, Jerez de la Frontera, Spain

Background: Crohn's disease (CD) has a negative impact on health related quality of life (HRQoL) and in the emotional status (ES). High levels of psychological distress have been reported in these patients that could be soften with a good social support. The aim of this study was to assess the influence of CD in the ES and HRQoL in a large sample of CD patients.

Methods: Multicenter, cross-sectional observational study. Patients were recruited between 2009 and 2010 through the Spanish CD patient association and by gastroenterologists. Socio-demographic and clinical information were recorded. An “ad hoc” ES scale (including concern about the illness, need of psychological support, and mood alterations) was performed. Total score ranges from 0 to 100, with higher scores reflecting a better status. HRQoL, work productivity and daily activity were assessed with the “Inflammatory Bowel Disease Questionnaire” (IBDQ9) and “Work Productivity and Activity Impairment Questionnaire” (WPAI). Finally, the “Overall Work Productivity Loss” (OWPL) and “Daily Activities Impairment” (DAI) were measured. ANOVA, chi-square and Pearson correlation were used.

Results: 1688 consecutive patients were recruited. 64% members of a CD association, 51% females, mean age 42.5 years (SD 11.2), 86.8% were diagnosed more than two years before and 19.1% underwent surgery in the previous two years. At the time of the survey, 38.5% reported active symptoms. Most patients were “much” or “enough” concerned about the future evolution of their illness (68.3%). Only a 3.6% were not worried at all. 42.7% had felt depressed or discouraged in the last 2 weeks before the interview and psychologists were consulted by 27%. Median rate of the emotional scale was 61.5 (SD 21.6). ES mean score was affected by relapses (57, SD 21.3) vs. 64.5 (SD 21.3) between relapses, and by the knowledge of the illness, ranging from not informed (32, SD 28) to much informed (63, SD 22.7). ES significantly influences the DAI (r = −0.6) and OWPL (r = −0.5). HRQoL was also significantly related with DAI (r = −0.7) and OWPL (r = −0.6).

Conclusions: Relapses and knowledge about the illness are closely related with the ES.

Patients would benefit from a good knowledge and control of the illness, leading to a better HRQoL, overall work productivity and daily activities.